Hybrid mathematical model of Leukemic diseases with resistance

Authors

  • Soumia Moulay, Abderrahmane Oumansour, Manel Yousra Zettam, Nacera Helal, Ghaouti Djellouli, Abdelkader Lakmeche, Mohamed Helal

Keywords:

Chronic myeloid leukemia, Resistance model, Partial differential equation, Ordinary differential equation, Steady states, Local stability, Numerical simulations.

Abstract

The main objective of this paper is to examine an hybrid mathematical model that addresses leukemia diseases with resistance. Initially, we construct the foundational model comprising three equations, with one accounting for age structure and the others representing ordinary differential equations. Subsequently, we delve into understanding the behavior of our solutions by investigating the existence and stability of steady states. To validate our findings, we conduct some numerical simulations.

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Published

2025-05-22

How to Cite

Soumia Moulay, Abderrahmane Oumansour, Manel Yousra Zettam, Nacera Helal, Ghaouti Djellouli, Abdelkader Lakmeche, Mohamed Helal. (2025). Hybrid mathematical model of Leukemic diseases with resistance. Journal of Computational Analysis and Applications (JoCAAA), 34(5), 13–37. Retrieved from https://eudoxuspress.com/index.php/pub/article/view/2808

Issue

Vol. 34 No. 5 (2025): JOCAAA

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.