Changes in extracellular collagen and caspase-3 expression in testis of male mice due to frequent exposure to magnetic resonance imaging (MRI); Histochemical and immunohistochemical studies
Keywords:
MRI, mice, testis, histopathology, collagen, caspase-3Abstract
Magnetic fields included in magnetic resonance imaging (MRI) technology are now utilized extensively in diagnostic medicine and healthcare applications. Simultaneously, it provides potential risks to human health, and their biological impacts on the human body are garnering heightened inquiry. The primary objective of the current study was to examine the biological effects of a high-strength magnetic field produced by 1.5 Tesla static magnetic fields on male mice spermatogenesis parameters in magnetic resonance imaging.
References
Although MRI remains a critical diagnostic tool, the biological effects on the testes, especially with prolonged exposure, warrant further investigation. Future studies should aim to elucidate the underlying mechanisms of MRI-induced testicular toxicity and explore strategies to mitigate potential risks associated with extended or frequent MRI exposure. Abtin, S., Seyedaghamiri, F., Aalidaei, Z., Farrokhi, A., Moshrefi, F., Ziveh, T., ... & Haghparast, A. (2024). A review on the consequences of molecular and genomic alterations following exposure to electromagnetic fields: Remodeling of neuronal network and cognitive changes. Brain Research Bulletin, 111090.
Aitken, R. J., & Roman, S. D. (2008). Antioxidant systems and oxidative stress in the testes. Molecular Mechanisms in Spermatogenesis, 154–171.
