Chemotherapy Induced Peripheral Neuropathy: Influence of Gabapentin On Quality Of Life

Authors

  • Sana Ahmed El Sayed Behery, Mostafa m. Toam, MW Hegazy, Enas Ibrahim Abdelhady, Rawda Balata

Keywords:

Chemotherapy, Induced Peripheral Neuropathy, Gabapentin,Quality Of Life

Abstract

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating side effect of neurotoxic chemotherapy agents, significantly affecting patients' quality of life (QoL). Gabapentin, a gamma-aminobutyric acid (GABA) analogue, has been explored as a potential intervention to mitigate CIPN-related symptoms. However, its efficacy in improving QoL remains debated.

References

Patel P, Rajput HS, Chavda K, et al. Assessing the effectiveness of gabapentin in paclitaxel-induced neuropathic pain: An observational, cohort study. J Oncol Pharm Pract. 2024.

Aghili M, Zare M, Mousavi N, et al. Efficacy of gabapentin for the prevention of paclitaxel-induced peripheral neuropathy: A randomized placebo-controlled clinical trial. Breast J. 2019;25(2):226-231.

Was H, Borkowska A, Bagues A, et al. Mechanisms of chemotherapy-induced neurotoxicity. Front Pharmacol.

;13:750507.

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Published

2024-06-11

How to Cite

Sana Ahmed El Sayed Behery, Mostafa m. Toam, MW Hegazy, Enas Ibrahim Abdelhady, Rawda Balata. (2024). Chemotherapy Induced Peripheral Neuropathy: Influence of Gabapentin On Quality Of Life . Journal of Computational Analysis and Applications (JoCAAA), 33(06), 1536–1545. Retrieved from https://eudoxuspress.com/index.php/pub/article/view/2200

Issue

Vol. 33 No. 06 (2024): JOCAAA

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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